Recent Publications

Book Chapters
Hoogstraten CG, Sumita M, White NA. “Unraveling the thermodynamics and kinetics of RNA assembly: surface plasmon resonance, isothermal titration calorimetry, and circular dichroism.” Methods Enzymol. (2014);549:407-32. doi:10.1016/B978-0-12-801122-5.00017-9

Hoogstraten CG, Sumita M. “Lead and RNA.” Encyclopedia of Metalloproteins. Uversky V, Kretsinger RH, Permyakov EA., eds. (2013);pp 1166-1173

Publications

White NA, Hoogstraten CG. “Thermodynamics and kinetics of RNA tertiary structure formation in the junctionless hairpin ribozyme.” Biophys Chem. (2017) Jul 8;228:62-68. doi: 10.1016/j.bpc.2017.07.001

Ochieng PO, White NA, Feig M, Hoogstraten CG. “Intrinsic Base-Pair Rearrangement in the Hairpin Ribozyme Directs RNA Conformational Sampling and Tertiary Interface Formation.” J Phys Chem B. (2016) Oct 5. doi:10.1021/acs.jpcb.6b05606

Hoogstraten CG, Sumita M, White NA. “Unraveling the thermodynamics and kinetics of RNA assembly: surface plasmon resonance, isothermal titration calorimetry, and circular dichroism.” Methods Enzymol. (2014) 549:407-32. doi:10.1016/B978-0-12-801122-5.00017-9

Sumita M, White NA, Julien KR, Hoogstraten CG. “Intermolecular domain docking in the hairpin ribozyme: metal dependence, binding kinetics and catalysis.” RNA Biol. (2013)Mar;10(3):425-35. doi:10.4161/rna.23609

Johnson JE Jr, Hoogstraten CG. “Extensive backbone dynamics in the GCAA RNA tetraloop analyzed using 13C NMR spin relaxation and specific isotope labeling.” J Am Chem Soc. (2008)Dec 10;130(49):16757-69. doi:10.1021/ja805759z

Julien KR, Sumita M, Chen PH, Laird-Offringa IA, Hoogstraten CG. “Conformationally restricted nucleotides as a probe of structure-function relationships in RNA.” RNA. (2008)Aug;14(8):1632-43. doi:10.1261/rna.866408

Hoogstraten CG, Johnson JE Jr. “Metabolic labeling: Taking advantage of bacterial pathways to prepare spectroscopically useful isotope patterns in proteins and nucleic acids.” Concepts in Magnetic Resonance Part A 32A.1 (2008); pp.34-55. doi:10.1002/(ISSN)1552-5023

Hoogstraten CG, Sumita M. “Structure-function relationships in RNA and RNP enzymes: recent advances.” Biopolymers. (2007)Dec 5-15;87(5-6):317-28. doi:10.1002/bip.20836

Vogt M, Lahiri S, Hoogstraten CG, Britt RD, DeRose VJ. “Coordination Environment of a Site-Bound Metal Ion in the Hammerhead Ribozyme Determined by.” Journal of the American Chemical Society (2006);128(51):16764-70. doi:10.1021/ja057035p

Johnson JE Jr, Julien KR, Hoogstraten CG. “Alternate-site isotopic labeling of ribonucleotides for NMR studies of ribose conformational dynamics in RNA.” J Biomol NMR. (2006)Aug;35(4):261-74. doi:10.1007/s10858-006-9041-x

Hoogstraten CG, Britt RD. “Water counting: quantitating the hydration level of paramagnetic metal ions bound to nucleotides and nucleic acids.” RNA. (2002)Feb;8(2):252-60.

Hoogstraten CG, Grant CV, Horton TE, DeRose VJ, Britt RD. “Structural analysis of metal ion ligation to nucleotides and nucleic acids using pulsed EPR spectroscopy.” J Am Chem Soc. (2002)Feb 6;124(5):834-42.