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Recent Publications

Vocelle D, Chan C, Walton SP. “Endocytosis Controls Small Interfering RNA Efficiency: Implications for Small Interfering RNA Delivery Vehicle Design and Cell-Specific Targeting.” Nucleic Acid Ther. (2019) Nov 12. doi: 10.1089/nat.2019.0804

Baek S, Liu C, Gou K, Kim J, Gharahi H, Chan C. “Utilization of the Theory of Small on Large Deformation for Studying Mechanosensitive Cellular Behaviors.” J Elast. (2019) Aug;136(2):137-157.

Dalgıç E, Konu Ö, Öz ZS, Chan C. “Lower connectivity of tumor coexpression networks is not specific to cancer.” In Silico Biol. (2019) May 30;13(1-2):41-53. doi: 10.3233/ISB-190472

Angart PA, Adu-Berchie K, Carlson RJ, Vocelle DB, Chan C, Walton SP. “Relative Quantification of siRNA Strand Loading into Ago2 for Design of Highly Active siRNAs.” Methods Mol Biol. (2019) May 17;1974:41-56. doi: 10.1007/978-1-4939-9220-1_4

Cho H, Stanzione F, Oak A, Kim GH, Yerneni S, Qi L, Sum AK, Chan C. “Intrinsic Structural Features of the Human IRE1α Transmembrane Domain Sense Membrane Lipid Saturation.” Cell Rep. (2019) Apr 2;27(1):307-320.e5. doi: 10.1016/j.celrep.2019.03.017

Thompson R, Casali C, Chan C. “Forskolin and IBMX Induce Neural Transdifferentiation of MSCs Through Downregulation of the NRSF.” Sci Rep. (2019) Feb 27;9(1):2969. doi: 10.1038/s41598-019-39544-0

Liu C, Kray J, Chan C. “Schwann Cells Enhance Penetration of Regenerated Axons into Three-Dimensional Microchannels.” Tissue Eng Regen Med. (2018) Jun;15(3):351-361. doi: 10.1007/s13770-018-0115-0

Thompson R, Chan C. “NRSF and Its Epigenetic Effectors: New Treatments for Neurological Disease.” Brain Sci. (2018) Dec 19;8:(12). doi: 10.3390/brainsci8120226

Liu C, Chan C. “An Approach to Enhance Alignment and Myelination of Dorsal Root Ganglion Neurons.” J Vis Exp. (2016) Aug 24;(114). doi:10.3791/54085

Bilgin B, Nath A, Chan C, Walton SP. “Characterization of transcription factor response kinetics in parallel.” BMC Biotechnol. (2016) Aug 24;16(1):62. doi:10.1186/s12896-016-0293-6

Liu C, Kray J, Toomajian V, Chan C. “Schwann Cells Migration on Patterned Polydimethylsiloxane Microgrooved Surface.” Tissue Eng Part C Methods. (2016) Jul;22(7):644-51. doi:10.1089/ten.TEC.2015.0539

Li X, Handee W, Kuo MH. “The slim, the fat, and the obese: guess who lives the longest?” Curr Genet. (2016) May 26. doi:10.1007/s00294-016-0617-z

Thompson R, Chan C. “Signal transduction of the physical environment in the neural differentiation of stem cells.” Technology (Singap World Sci). (2016) Mar;4(1):1-8. doi: 10.1142/S2339547816400070

Vocelle D, Chesniak OM, Malefyt AP, Comiskey G, Adu-Berchie K, Smith MR 3rd, Chan C, Walton SP. “Dextran functionalization enhances nanoparticle-mediated siRNA delivery and silencing.” Technology (Singap World Sci). (2016) Mar;4:(1). doi: 10.1142/S2339547816400100

Stapleton JA, Kim J, Hamilton JP, Wu M, Irber LC, Maddamsetti R, Briney B, Newton L, Burton DR, Brown CT, Chan C, Buell CR, Whitehead TA. “Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing.” PLoS One. (2016) Jan 20;11(1):e0147229. doi: 10.1371/journal.pone.0147229

Nath A, Chan C. “Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers.” Sci Rep. (2016) Jan 4;6:18669. doi: 10.1038/srep18669

Liu C, Pyne R, Kim J, Wright NT, Baek S, Chan C. “The Impact of Prestretch Induced Surface Anisotropy on Axon Regeneration.” Tissue Eng Part C Methods. (2016) Jan 8. doi:10.1089/ten.TEC.2015.0328

Nath A, Li I, Roberts LR, Chan C.“ Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma.” Sci Rep. (2015) Oct 1;5:14752. doi: 10.1038/srep14752

Vocelle D, Chan C, Walton SP. “How can novel microscopic approaches shed light on the function of nucleic acid-based drugs?” Future Med Chem. (2015) Sep;7(13):1623-5. doi: 10.4155/fmc.15.110

Kowalsky CA, Faber MS, Nath A, Dann HE, Kelly VW, Liu L, Shanker P, Wagner EK, Maynard JA, Chan C, Whitehead TA. “Rapid fine conformational epitope mapping using comprehensive mutagenesis and deep sequencing.” J Biol Chem. (2015) Oct 30;290(44):26457-70. doi: 10.1074/jbc.M115.676635

Hejase HA, Chan C. “Improving Drug Sensitivity Prediction Using Different Types of Data. ” CPT Pharmacometrics Syst Pharmacol. (2015) Feb;4(2):e2. doi: 10.1002/psp4.2

Lynam DA, Shahriari D, Wolf KJ, Angart PA, Koffler J, Tuszynski MH, Chan C, Walton P, Sakamoto J.“ Brain derived neurotrophic factor release from layer-by-layer coated agarose nerve guidance scaffolds.” Acta Biomater. (2015) May;18:128-31. doi: 10.1016/j.actbio.2015.02.014

Zhang L, Liu L, Thompson R, Chan C.“ CREB modulates calcium signaling in cAMP-induced bone marrow stromal cells (BMSCs).” Cell Calcium. (2014) Oct;56(4):257-68. doi: 10.1016/j.ceca.2014.07.013

Fang L, Cho HJ, Chan C, Feig M. “Binding site multiplicity with fatty acid ligands: implications for the regulation of PKR kinase autophosphorylation with palmitate.” Proteins. (2014) Oct;82(10):2429-42. doi: 10.1002/prot.24607