Recent Publications

Shen L, Inoue A, He J, Liu, Y, Lu F, and Zhang Y. “Tet3 and DNA replication mediate demethylation of both maternal and paternal genomes in mouse zygotes.” Cell Stem Cell. (2014) 15(4):459-70 doi:10.1016/j.stem.2014.09.002

He J, Shen L, Wan M, Taranova O, Wu H, Zhang Y. “Kdm2b maintains murine embryonic stem cells status by recruiting PRC1 complex to CpG islands of developmental genes.” Nat Cell Biol. (2013) 15(4) 373-84. doi:10.1038/ncb2702

Liang G, He J, Zhang Y. “Kdm2b promotes induced pluripotent stem cell generation by facilitating gene activation during early stage of reprogramming.” Nat Cell Biol. (2012) 14(5):457-66. doi:10.1038/ncb2483

Nguyen AT, He J, Taranova O, and Zhang Y. “Essential role of DOT1L in maintaining normal adult hematopoiesis.” Cell Res. (2011) 21:1370-1373. doi:10.1038/cr.2011.115

Nguyen AT, Taranova O, He J, Zhang Y. “DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.” Blood. (2011) 117(25):6912-6922. doi:10.1182/blood-2011-02-334359

He J, Nguyen AT, Zhang Y “KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia.” Blood. (2011) 117(14):3869-3880. doi:10.1182/blood-2010-10-312736

He J, Kallin EM, Tsukada Y, Zhang Y. “The H3K36 Demethylase Jhdm1b/Kdm2b Regulates Cell Proliferation and Senescence through p15Ink4b.” Nature Structural & Molecular Biology. (2008) 15(11):1169-75. doi:10.1038/nsmb.1499

Tateishi K, He J, Taranova O, Liang G, D'Alessio AC, Zhang Y. “Generation of Insulin-Secreting Islet-like Clusters from Human Skin Fibroblasts.” JBC. (2008) 283(46):31601-7.  doi:10.1074/jbc.M806597200

He J, Yang Q, Chang LJ. “Dynamic DNA methylation and histone modifications contribute to lentiviral transgene silencing in murine embryonic carcinoma cells.” J Virol. (2005) 79:13497-508. doi:10.1128/JVI.79.21.13497-13508.2005

He J, Chang LJ. “Functional characterization of hepatoma-specific stem cell antigen-2.” Mol Carcinog. (2004) 40:90-103. doi:10.1002/mc.20019