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Latest Publications

CoA Recycling by a Benzoate Coenzyme A Ligase in Cascade Reactions with Aroyltransferases to Biocatalyze Paclitaxel Analogs, S.A. Sullivan, ; I.N. Nawarathne; K.D. Walker. Arch. Biochem. Biophys. 2020, (accepted). DOI: 10.1016/

Exploring the Scope of an α/β-Aminomutase for the Amination of Cinnamate Epoxides to Arylserines and Arylisoserines, P.K. Shee; N.D. Ratnayake; T. Walter; O. Goethe; E.N. Onyeozili; K.D. Walker. ACS Catal. 2019, 9, 7418-7430. DOI: 10.1021/acscatal.9b01557

Understanding Which Residues of the Active Site and Loop Structure of a Tyrosine Aminomutase Define its Mutase and Lyase Activities, G. Attanayake; T. Walter; K. D. Walker. Biochemistry (ACS), 201857 (25), 3503-3514 DOI: 10.1021/acs.biochem.8b00269.

in Special Issue: Current Topics in Mechanistic Enzymology 

Biosynthesis of Paclitaxel Intermediate
Kevin Walker, Patent No. US 9732365 B2 (US20150284751WO2013191678A1), Aug 15, 2017, Asignee: Michigan State University

Biocatalysis of a Paclitaxel Analogue: Conversion of Baccatin III to N-Debenzoyl-N-(2-furoyl)paclitaxel and Characterization of an Amino Phenylpropanoyl CoA Transferase. C.K. Thornburg; T. Walter;  K.D. Walker. Biochemistry (ACS) 201756 (44), 5920–5930. DOI: 10.1021/acs.biochem.7b00912.

Paclitaxel Biosynthesis: Adenylation and Thiolation Domains of an NRPS TycA PheAT Module Produce Various Arylisoserine CoA Thioesters. R. Muchiri; K.D. Walker. 2017, Biochemistry (ACS)  56 (10), 1415–1425: DOI: 10.1021/acs.biochem.6b01188.

Identification and characterization of the missing phosphatase on the riboflavin biosynthesis pathway in Arabidopsis thaliana. N. Sa; R. Rawat; C.K. Thornburg; K.D. Walker; S. Roje. 2016, Plant J. 88 (5), 705–716 DOI: 10.1111/tpj.13291 Featured Article.