Recent Publications

Hiser C, Liu J, Ferguson-Miller S. “The K-path entrance in cytochrome c oxidase is defined by mutation of E101 and controlled by an adjacent ligand binding domain.” Biochim Biophys Acta. (2018) Apr 4. doi: 10.1016/j.bbabio.2018.03.017

Liu J, Hiser C, Ferguson-Miller S. “Role of conformational change and K-path ligands in controlling cytochrome c oxidase activity.” Biochem Soc Trans. (2017) Aug 24;. doi: 10.1042/BST20160138

Li F, Liu J, Liu N, Kuhn LA, Garavito RM, Ferguson-Miller S. “Translocator Protein 18 kDa (TSPO): An Old Protein with New Functions?” Biochemistry. (2016) May 9;. doi:10.1021/acs.biochem.6b00142

Li F, Liu J, Zheng Y, Garavito RM, Ferguson-Miller S. “Response to Comment on "Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism".” Science. (2015) Oct 30;350(6260):519. doi:10.1126/science.aab2595

Hwang HJ, Lynn SG, Vengellur A, Saini Y, Grier EA, Ferguson-Miller SM, LaPres JJ. “Hypoxia Inducible Factors Modulate Mitochondrial Oxygen Consumption and Transcriptional Regulation of Nuclear-Encoded Electron Transport Chain Genes.” Biochemistry. (2015) Jun 23;54(24):3739-48. doi:10.1021/bi5012892

Li F, Liu J, Garavito RM, Ferguson-Miller S. “Evolving understanding of translocator protein 18 kDa (TSPO).” Pharmacol Res. (2015) Sep;99:404-9. doi:10.1016/j.phrs.2015.03.022

Li F, Liu J, Valls L, Hiser C, Ferguson-Miller S. “Identification of a key cholesterol binding enhancement motif in translocator protein 18 kDa.” Biochemistry. (2015) Feb 24;54(7):1441-3. doi:10.1021/bi5015453

Li F, Liu J, Zheng Y, Garavito RM, Ferguson-Miller S. “Protein structure. Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.” Science. (2015) Jan 30;347(6221):555-8. doi:10.1126/science.1260590

Schwaighofer A, Ferguson-Miller S, Naumann RL, Knoll W, Nowak C. “Phase-sensitive detection in modulation excitation spectroscopy applied to potential induced electron transfer in cytochrome c oxidase.” Appl Spectrosc. (2014);68(1):5-13. doi:10.1366/13-07188

Buhrow L, Hiser C, Van Voorst JR, Ferguson-Miller S, Kuhn LA. “Computational prediction and in vitro analysis of potential physiological ligands of the bile acid binding site in cytochrome c oxidase.” Biochemistry. (2013) Oct 8;52(40):6995-7006. doi:10.1021/bi400674h

Li F, Xia Y, Meiler J, Ferguson-Miller S. “Characterization and modeling of the oligomeric state and ligand binding behavior of purified translocator protein 18 kDa from Rhodobacter sphaeroides.” Biochemistry. (2013) Aug 27;52(34):5884-99. doi:10.1021/bi400431t

Hiser C, Buhrow L, Liu J, Kuhn L, Ferguson-Miller S. “A conserved amphipathic ligand binding region influences k-path-dependent activity of cytochrome C oxidase.” Biochemistry. (2013) Feb 26;52(8):1385-96. doi:10.1021/bi3014505

Szundi I, Funatogawa C, Cassano J, McDonald W, Ray J, Hiser C, Ferguson-Miller S, Gennis RB, Einarsdóttir Ó. “Spectral identification of intermediates generated during the reaction of dioxygen with the wild-type and EQ(I-286) mutant of Rhodobacter sphaeroides cytochrome c oxidase.” Biochemistry. (2012) Nov 20;51(46):9302-11. doi:10.1021/bi301166u

Buhrow L, Ferguson-Miller S, Kuhn LA. “From static structure to living protein: computational analysis of cytochrome c oxidase main-chain flexibility.” Biophys J. (2012) May 2;102(9):2158-66. doi:10.1016/j.bpj.2012.03.040

Zhang X, Fhaner CJ, Ferguson-Miller SM, Reid GE. “Evaluation of ion activation strategies and mechanisms for the gas-phase fragmentation of sulfoquinovosyldiacylglycerol lipids from Rhodobacter sphaeroides.” Int J Mass Spectrom. (2012) Apr 15;316-318:100-107. doi:10.1016/j.ijms.2012.01.011

Ferguson-Miller S, Hiser C, Liu J. “Gating and regulation of the cytochrome c oxidase proton pump.” Biochim Biophys Acta. (2012) Apr;1817(4):489-94. doi:10.1016/j.bbabio.2011.11.018