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Protein Structure and Molecular Biophysics

Researchers in this focus area probe molecular structure to understand binding and catalysis by biological molecules and design or discover new ligands to enhance or suppress function, for biomedical and biotechnology applications. X-ray crystallography, nuclear magnetic and electron paramagnetic resonance, visual spectroscopy, fluorescence and visual microscopy, circular dichroism, confocal laser scanning microscopy, computational and mathematical modeling, mass spectrometry, organic synthesis, and recombinant DNA techniques are among the broad range of methods used.