Recent Publications
Saha S, Patra P, Igoshin O, Kroos L. “Systematic analysis of the Myxococcus xanthus developmental gene regulatory network supports posttranslational regulation of FruA by C-signaling.” Mol Microbiol. (2019) Mar 20;. doi: 10.1111/mmi.14249
Hoang Y, Kroos L. “Ultrasensitive response of developing Myxococcus xanthus to the addition of nutrient medium correlates with the level of MrpC.” J Bacteriol. (2018) Sep 4. doi: 10.1128/JB.00456-18
Halder S, Parrell D, Whitten D, Feig M, Kroos L. “Interaction of intramembrane metalloprotease SpoIVFB with substrate Pro-σK.” Proc Natl Acad Sci U S A. (2017) Nov 27. doi: 10.1073/pnas.1711467114
Parrell D, Zhang Y, Olenic S, Kroos L. “Bacillus subtilis Intramembrane Protease RasP Activity in Escherichia coli and in Vitro.” J Bacteriol. (2017) Jul 3. pii: JB.00381-17. doi: 10.1128/JB.00381-17
Rajagopalan R, Kroos L. “The dev Operon Regulates the Timing of Sporulation during Myxococcus xanthus Development.” J Bacteriol. (2017) Mar 6. pii: JB.00788-16. doi: 10.1128/JB.00788-16
Kroos L. “Highly Signal-Responsive Gene Regulatory Network Governing Myxococcus Development.” Trends Genet. (2016) Dec 1. pii: S0168-9525(16)30145-7. doi: 10.1016/j.tig.2016.10.006
Zhang Y, Halder S, Kerr RA, Parrell D, Ruotolo B, Kroos L. “Complex Formed between Intramembrane Metalloprotease SpoIVFB and Its Substrate Pro-σK.” J Biol Chem. (2016) Mar 7;. doi:10.1074/jbc.M116.715508
Rajagopalan R, Wielgoss S, Lippert G, Velicer GJ, Kroos L. “devI is an evolutionarily young negative regulator of Myxococcus xanthus development.” J Bacteriol. (2015)Apr;197(7):1249-62. doi:10.1128/JB.02542-14
Robinson M, Son B, Kroos D, Kroos L. “Transcription factor MrpC binds to promoter regions of hundreds of developmentally-regulated genes in Myxococcus xanthus.” BMC Genomics. (2014)Dec 16;15:1123. doi:10.1186/1471-2164-15-1123
Campbell A, Viswanathan P, Barrett T, Son B, Saha S, Kroos L. “Combinatorial regulation of the dev operon by MrpC2 and FruA during Myxococcus xanthus development.” J Bacteriol. (2015)Jan;197(2):240-51. doi:10.1128/JB.02310-14
Rajagopalan R, Kroos L. “Nutrient-regulated proteolysis of MrpC halts expression of genes important for commitment to sporulation during Myxococcus xanthus development.” J Bacteriol. (2014)Aug;196(15):2736-47. doi:10.1128/JB.01692-14
Chen B, Himes P, Liu Y, Zhang Y, Lu Z, Liu A, Yan H, Kroos L. “Structure of bacterial transcription factor SpoIIID and evidence for a novel mode of DNA binding.” J Bacteriol. (2014)Jun;196(12):2131-42. doi:10.1128/JB.01486-13
Konovalova A, Søgaard-Andersen L, Kroos L. “Regulated proteolysis in bacterial development.” FEMS Microbiol Rev. (2014)May;38(3):493-522. doi:10.1111/1574-6976.12050
Kroos L, Akiyama Y. “Biochemical and structural insights into intramembrane metalloprotease mechanisms.” Biochim Biophys Acta. (2013)Dec;1828(12):2873-85. doi:10.1016/j.bbamem.2013.03.032
Zhang Y, Luethy PM, Zhou R, Kroos L. “Residues in conserved loops of intramembrane metalloprotease SpoIVFB interact with residues near the cleavage site in pro-αK.” J Bacteriol. (2013)Nov;195(21):4936-46. doi:10.1128/JB.00807-13
Zhou R, Chen K, Xiang X, Gu L, Kroos L. “Features of Pro-αK important for cleavage by SpoIVFB, an intramembrane metalloprotease.” J Bacteriol. (2013)Jun;195(12):2793-806. doi:10.1128/JB.00229-13
Son B, Liu Y, Kroos L. “Combinatorial regulation by MrpC2 and FruA involves three sites in the fmgE promoter region during Myxococcus xanthus development.” J Bacteriol. (2011)Jun;193(11):2756-66. doi:10.1128/JB.00205-11
Imamura D, Kuwana R, Kroos L, Feig M, Takamatsu H, Watabe K. “Substrate specificity of SpoIIGA, a signal-transducing aspartic protease in Bacilli.” J Biochem. (2011)Jun;149(6):665-71. doi:10.1093/jb/mvr027
Lee JS, Son B, Viswanathan P, Luethy PM, Kroos L. “Combinatorial regulation of fmgD by MrpC2 and FruA during Myxococcus xanthus development.” J Bacteriol. (2011)Apr;193(7):1681-9. doi:10.1128/JB.01541-10