Recent Publications
Zhen Fang, Michael G. Flynn, James E. Jackson, and Eric L. Hegg. “Thio-assisted reductive electrolytic cleavage of lignin β-O-4 models and authentic lignin.” Green Chemistry. (2021) 23, 412-421. doi: 10.1039/D0GC03597A
G. E. Klinger, Y. Zhou, J. A. Foote, A. M. Wester, Y. Cui, M. Alherech, S. S. Stahl, J. E. Jackson, E. L. Hegg. Nucleophilic Thiols Reductively Cleave Ether Linkages in Lignin Model Polymers and Lignin. ChemSusChem 2020, 13, 4394.
Julius Campeciño, Satyanarayana Lagishetty, Zdzislaw Wawrzak, Victor Sosa Alfaro, Nicolai Lehnert, Gemma Reguera, Jian Hu, and Eric L. Hegg. Cytochrome c nitrite reductase from the bacterium Geobacter lovleyi represents a new NrfA subclass. J. Biol. Chem. 295, 11455-11465.
Zhen Fang*, Saeid Nikafshar, Eric L. Hegg, and Mojgan Nejad. Biobased Divanillin As a Precursor for Formulating Biobased Epoxy Resin. ACS Sustainable Chemistry & Engineering 2020 8 (24), 9095-9103.
Zhou, Y.; Klinger, G.E.; Hegg, E.L.; Saffron, C.M.; Jackson, J.E.* “Multiple Mechanisms Mapped in Aryl Alkyl Ether Cleavage via Aqueous Electrocatalytic Hydrogenation (ECH) over Skeletal Nickel.” J. Am. Chem. Soc. 2020, 142, 4037-4050.
Srivastava1, P.A.; Hegg, E.L.; Fox, B.G.; Yennamalli, R.M.* “PreDSLpmo: A Neural Network-Based Prediction Tool for Functional Annotation of Lytic Polysaccharide Monooxygenases.” J. Biotechnol. 2020, 308, 148-155.
Bhalla A, Cai CM, Xu F, Singh SK, Bansal N, Phongpreecha T, Dutta T, Foster CE, Kumar R, Simmons BA, Singh S, Wyman CE, Hegg EL, Hodge DB. “Performance of three delignifying pretreatments on hardwoods: hydrolysis yields, comprehensive mass balances, and lignin properties.” Biotechnol Biofuels. (2019) Sep 9;12:213. doi: 10.1186/s13068-019-1546-0
Klinger GE, Zhou Y, Hao P, Robbins J, Aquilina JM, Jackson JE, Hegg EL. “Biomimetic Reductive Cleavage of Keto Aryl Ether Bonds by Small Molecule Thiols.” ChemSusChem. (2019) Aug 16. doi: 10.1002/cssc.201901742
Yuan Z, Singh SK, Bals B, Hodge DB, Hegg EL. “Integrated Two-Stage Alkaline–Oxidative Pretreatment of Hybrid Poplar. Part 2: Impact of Cu-Catalyzed Alkaline Hydrogen Peroxide Pretreatment Conditions on Process Performance and Economics.” Ind. Eng. Chem. Res. (2019) Aug 5. doi: 10.1021/acs.iecr.9b00901
Singh SK, Savoy AW, Yuan Z, Luo H, Stahl SS, Hegg EL, Hodge DB. “Integrated Two-Stage Alkaline-Oxidative Pretreatment of Hybrid Poplar. Part 1: Impact of Alkaline Pre-Extraction Conditions on Process Performance and Lignin Properties.” Ind. Eng. Chem. Res. (2019) Jun 5. doi: 10.1021/acs.iecr.9b01124
Herwaldt EJ, Rivett ED, White AJ, Hegg EL. “Cox15 interacts with the cytochrome bc1 dimer within respiratory supercomplexes as well as in the absence of cytochrome c oxidase.” J Biol Chem. (2018) Sep 4. doi: 10.1074/jbc.RA118.002496
Haslun JA, Ostrom NE, Hegg EL, Ostrom PH. “Estimation of Isotope Variation of N2O during Denitrification by Pseudomonas aureofaciens and Pseudomonas chlororaphis: Implications for N2O Source Apportionment.” Biogeosciences. (2018) Jun 27. 15:3873-3882. doi: 10.5194/bg-15-3873-2018
Yuan Z, Li G, Hegg EL. “Enhancement of sugar recovery and ethanol production from wheat straw through alkaline pre-extraction followed by steam pretreatment.” Bioresour Technol. (2018) Jun 21;266:194-202. doi: 10.1016/j.biortech.2018.06.065
Bhalla A, Fasahati P, Particka CA, Assad AE, Stoklosa RJ, Bansal N, Semaan R, Saffron CM, Hodge DB, Hegg EL. “Integrated experimental and technoeconomic evaluation of two-stage Cu-catalyzed alkaline-oxidative pretreatment of hybrid poplar.” Biotechnol Biofuels. (2018) May 17. 11:143. doi: 10.1186/s13068-018-1124-x
Bhalla A, Bansal N, Pattathil S, Li M, Shen W, Particka CA, Karlen SD, Phongpreecha T, Semaan RR, Gonzales-Vigil E, Ralph J, Mansfield SD, Ding SY, Hodge DB, Hegg EL. ”Engineered Lignin in Poplar Biomass Facilitates Cu-Catalyzed Alkaline-Oxidative Pretreatment&lduo; ACS Sustainable Chemistry & Engineering (2018) Jan 22;6(3):2932-2941 doi: 10.1021/acssuschemeng.7b02067
Das A, Rahimi A, Ulbrich A, Alherech M, Motagamwala AH, Bhalla A, da Costa Sousa L, Balan V, Dumesic JA, Hegg EL, Dale BE, Ralph J, Coon JJ, Stahl SS. ”Lignin Conversion to Low-Molecular-Weight Aromatics via an Aerobic Oxidation-Hydrolysis Sequence: Comparison of Different Lignin Sources&dlquo; ACS Sustainable Chemistry & Engineering (2018) Jan 19;6(3):3367-3374 doi: 10.1021/acssuschemeng.7b03541
Cornish AJ, Ginovska B, Thelen A, da Silva JC, Soares TA, Raugei S, Dupuis M, Shaw WJ, Hegg EL. “Single-Amino Acid Modifications Reveal Additional Controls on the Proton Pathway of [FeFe]-Hydrogenase.” Biochemistry. (2016) Jun 7;55(22):3165-73. doi: 10.1021/acs.biochem.5b01044
Bhalla A, Bansal N, Stoklosa RJ, Fountain M, Ralph J, Hodge DB, Hegg EL. “Effective alkaline metal-catalyzed oxidative delignification of hybrid poplar.” Biotechnol Biofuels. (2016);9:34. doi: 10.1186/s13068-016-0442-0
Yang H, Gandhi H, Moran JJ, Kreuzer HW, Ostrom NE, Hegg, EL. “Isotopic Fractionation Associated with [NiFe]- and [FeFe]-Hydrogenases.” Rapid Commun. Mass. Spectrom. (2016), 30, 285-292. doi: 10.1002/rcm.7432
Bansal, N, Bhalla A, Pattathil S, Adelman SL, Hahn MG, Hodge DB, Hegg EL. “Cell Wall-Associated Transition Metals Improve Alkaline-Oxidative Pretreatment in Diverse Hardwoods.” Green Chem. (2016), 18, 1405-1415. doi: 10.1039/C5GC01748C
Aussignargues C, Pandelia ME, Sutter M, Plegaria JS, Zarzycki J, Turmo A, Huang J, Ducat DC, Hegg EL, Gibney BR, Kerfeld CA. “Structure and Function of a Bacterial Microcompartment Shell Protein Engineered to Bind a [4Fe-4S] Cluster.” J Am Chem Soc. (2016) Apr 27;138(16):5262-70. doi: 10.1021/jacs.5b11734
Li Z, Bansal N, Azarpira A, Bhalla A, Chen CH, Ralph J, Hegg EL, Hodge DB. “Chemical and structural changes associated with Cu-catalyzed alkaline-oxidative delignification of hybrid poplar.” Biotechnol Biofuels. (2015);8:123. doi: 10.1186/s13068-015-0300-5
Cornish AJ, Green R, G‰rtner K, Mason S, Hegg EL. “Characterization of Hydrogen Metabolism in the Multicellular Green Alga Volvox carteri.” PLoS One. (2015);10(4):e0125324. doi: 10.1371/journal.pone.0125324
Yang H, Gandhi H, Ostrom NE, Hegg EL. “Isotopic fractionation by a fungal P450 nitric oxide reductase during the production of N2O.” Environ Sci Technol. (2014) Sep 16;48(18):10707-15. doi: 10.1021/es501912d
Quaroni L, Zlateva T, Sarafimov B, Kreuzer HW, Wehbe K, Hegg EL, Cinque G. “Synchrotron based infrared imaging and spectroscopy via focal plane array on live fibroblasts in D2O enriched medium.” Biophys Chem. (2014) May;189:40-8. doi: 10.1016/j.bpc.2014.03.002
Hildenbeutel M, Hegg EL, Stephan K, Gruschke S, Meunier B, Ott M. “Assembly factors monitor sequential hemylation of cytochrome b to regulate mitochondrial translation.” J Cell Biol. (2014) May 26;205(4):511-24. doi: 10.1083/jcb.201401009
Kreuzer HW, Hill EA, Moran JJ, Bartholomew RA, Yang H, Hegg EL. “Contributions of the [NiFe]- and [FeFe]-hydrogenase to H2 production in Shewanella oneidensis MR-1 as revealed by isotope ratio analysis of evolved H(2).” FEMS Microbiol Lett. (2014) Mar;352(1):18-24. doi: 10.1111/1574-6968.12361
Li Z, Chen CH, Hegg EL, Hodge DB. “Rapid and effective oxidative pretreatment of woody biomass at mild reaction conditions and low oxidant loadings.” Biotechnol Biofuels. (2013) Aug 26;6(1):119. doi: 10.1186/1754-6834-6-119
MacGregor BJ, Biddle JF, Siebert JR, Staunton E, Hegg EL, Matthysse AG, Teske A. “Why orange Guaymas Basin Beggiatoa spp. are orange: single-filament-genome-enabled identification of an abundant octaheme cytochrome with hydroxylamine oxidase, hydrazine oxidase, and nitrite reductase activities.” Appl Environ Microbiol. (2013) Feb;79(4):1183-90. doi: 10.1128/AEM.02538-12
Li Z, Chen CH, Liu T, Mathrubootham V, Hegg EL, Hodge DB. “Catalysis with Cu(II) (bpy) improves alkaline hydrogen peroxide pretreatment.” Biotechnol Bioeng. (2013) Apr;110(4):1078-86. doi: 10.1002/bit.24793
Vieler A, Wu G, Tsai CH, Bullard B, Cornish AJ, Harvey C, Reca IB, Thornburg C, Achawanantakun R, Buehl CJ, Campbell MS, Cavalier D, Childs KL, Clark TJ, Deshpande R, Erickson E, Armenia Ferguson A, Handee W, Kong Q, Li X, Liu B, Lundback S, Peng C, Roston RL, Sanjaya, Simpson JP, Terbush A, Warakanont J, Zäuner S, Farre EM, Hegg EL, Jiang N, Kuo MH, Lu Y, Niyogi KK, Ohlrogge J, Osteryoung KW, Shachar-Hill Y, Sears BB, Sun Y, Takahashi H, Yandell M, Shiu SH, Benning C. “Genome, functional gene annotation, and nuclear transformation of the heterokont oleaginous alga Nannochloropsis oceanica CCMP1779.” PLoS Genet. (2012);8(11):e1003064. doi: 10.1371/journal.pgen.1003064
Gärtner K, Lechno-Yossef S, Cornish AJ, Wolk CP, Hegg EL. “Expression of Shewanella oneidensis MR-1 [FeFe]-hydrogenase genes in Anabaena sp. strain PCC 7120.” Appl Environ Microbiol. (2012) Dec;78(24):8579-86. doi: 10.1128/AEM.01959-12