Recent Publications
Liban TJ, Medina EM, Tripathi S, Sengupta S, Henry RW, Buchler NE, Rubin SM. “Conservation and divergence of C-terminal domain structure in the retinoblastoma protein family.” Proc Natl Acad Sci U S A. (2017) Apr 24. pii: 201619170. doi: 10.1073/pnas.1619170114
Payankaulam S, Yeung K, McNeill H, Henry RW, Arnosti DN. “Regulation of cell polarity determinants by the Retinoblastoma tumor suppressor protein.” Sci Rep. (2016) Mar 14;6:22879. doi:10.1038/srep22879
Sengupta S, Henry RW. “Regulation of the retinoblastoma-E2F pathway by the ubiquitin-proteasome system.” Biochim Biophys Acta. (2015)Oct;1849(10):1289-97. doi:10.1016/j.bbagrm.2015.08.008
Wei Y, Mondal SS, Mouawad R, Wilczynski B, Henry RW, Arnosti DN. “Genome-Wide Analysis of Drosophila RBf2 Protein Highlights the Diversity of RB Family Targets and Possible Role in Regulation of Ribosome Biosynthesis.” G3 (Bethesda). (2015)May 20;5(7):1503-15. doi:10.1534/g3.115.019166
Sengupta S, Lingnurkar R, Carey TS, Pomaville M, Kar P, Feig M, Wilson CA, Knott JG, Arnosti DN, Henry RW. “The Evolutionarily Conserved C-terminal Domains in the Mammalian Retinoblastoma Tumor Suppressor Family Serve as Dual Regulators of Protein Stability and Transcriptional Potency.” J Biol Chem. (2015)Jun 5;290(23):14462-75. doi:10.1074/jbc.M114.599993
Elenbaas JS, Mouawad R, Henry RW, Arnosti DN, Payankaulam S. “Role of Drosophila retinoblastoma protein instability element in cell growth and proliferation.” Cell Cycle. (2015);14(4):589-97. doi:10.4161/15384101.2014.991182
Zhang L, Wei Y, Pushel I, Heinze K, Elenbaas J, Henry RW, Arnosti DN. “Integrated stability and activity control of the Drosophila Rbf1 retinoblastoma protein.” J Biol Chem. (2014)Sep 5;289(36):24863-73. doi:10.1074/jbc.M114.586818
Lansdell TA, Hurchla MA, Xiang J, Hovde S, Weilbaecher KN, Henry RW, Tepe JJ. “Noncompetitive modulation of the proteasome by imidazoline scaffolds overcomes bortezomib resistance and delays MM tumor growth in vivo.” ACS Chem Biol. (2013)Mar 15;8(3):578-87. doi:10.1021/cb300568r
Acharya P, Negre N, Johnston J, Wei Y, White KP, Henry RW, Arnosti DN. “Evidence for autoregulation and cell signaling pathway regulation from genome-wide binding of the Drosophila retinoblastoma protein.” G3 (Bethesda). (2012)Nov;2(11):1459-72. doi:10.1534/g3.112.004424
Raj N, Zhang L, Wei Y, Arnosti DN, Henry RW. “Ubiquitination of retinoblastoma family protein 1 potentiates gene-specific repression function.” J Biol Chem. (2012)Dec 7;287(50):41835-43. doi:10.1074/jbc.M112.422428
Gjidoda A, Henry RW. “RNA polymerase III repression by the retinoblastoma tumor suppressor protein.” Biochim Biophys Acta. (2013)Mar-Apr;1829(3-4):385-92. doi:10.1016/j.bbagrm.2012.09.011
Raj N, Zhang L, Wei Y, Arnosti DN, Henry RW. “Rbf1 degron dysfunction enhances cellular DNA replication.” Cell Cycle. (2012)Oct 15;11(20):3731-8. doi:10.4161/cc.21665
Lansdell TA, O'Reilly S, Woolliscroft T, Azevedo LM, Kahlon DK, Hovde S, McCormick JJ, Henry RW, Cornicelli JA, Tepe JJ. “Attenuation of collagen-induced arthritis by orally available imidazoline-based NF-κB inhibitors.” Bioorg Med Chem Lett. (2012)Jul 15;22(14):4816-9. doi:10.1016/j.bmcl.2012.05.056
Selvakumar T, Gjidoda A, Hovde SL, Henry RW. “Regulation of human RNA polymerase III transcription by DNMT1 and DNMT3a DNA methyltransferases.” J Biol Chem. (2012)Mar 2;287(10):7039-50. doi:10.1074/jbc.M111.285601