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Recent Publications

Gao Y, Aljazi MB, He J*. Neural hyperactivity is a core pathophysiological change induced by deletion of a high autism risk gene Ash1l in the mouse brain. Front Behav Neurosci. 2022 Apr 5;16:873466. doi: 10.3389/fnbeh.2022.873466. eCollection 2022.PMID: 35449559.

Aljazi MB, Gao Y, Wu Y, He J*. SMYD5 is a histone H3-specific methyltransferase mediating mono-methylation of histone H3 lysine 36 and 37. Biochemical and Biophysical Research Communications. 2022 Apr 9;599:142-147. Epub 2022 Feb 12. PMID: 35182940.

Gao Y, Duque-Wilckens N, Aljazi MB, Moeser AJ, Mias GI, Robison AJ, Zhang Y*, He J*. Impaired KDM2B-mediated PRC1 recruitment to chromatin causes defective neural stem cell self-renewal and ASD/ID-like behaviors. iScience. 2022;25(2):103742. Epub 2022/02/08. doi: 10.1016/j.isci.2022.103742. PubMed PMID: 35128353; PMCID: PMC8800019.

Aljazi MB, Gao Y, Wu Y, Mias GI, He J*. Histone H3K36me2-specific methyltransferase ASH1L promotes MLL-AF9-induced leukemogenesis. Front Oncol. 2021;11:754093. PubMed Central PMCID: PMC8534482. 

Gao Y, Aljazi MB, Wu Y, He J*. Vorinostat, a histone deacetylase inhibitor, ameliorates the sociability and cognitive memory in an Ash1L-deletion-induced ASD/ID mouse model. Neurosci Lett. 2021 Sep 9:136241. doi: 10.1016/j.neulet.2021.136241. PMID: 34509565.

Gao Y, Duque-Wilckens N, Aljazi MB, Wu Y, Moeser AJ, Mias GI, Robison AJ, He J*. Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors. Commun Biol. 2021 Jun 18;4(1):756. doi: 10.1038/s42003-021-02282-z.PMID: 34145365. 

Aljazi MB, Gao Y, Wu Y, Mias GI, He J*. Cell signaling coordinates global PRC2 recruitment and developmental gene expression in murine embryonic stem cells. iScience. 2020;23(11):101646. Epub 2020/10/27. doi: 10.1016/j.isci.2020.101646. PubMed PMID: 33103084; PMCID: PMC7578752.

Mias GI*, Singh VV, Rogers LRK, Xue S, Zheng M, Domanskyi S, Kanada M, Piermarocchi C, He J. Longitudinal saliva omics responses to immune perturbation: a case study. Sci Rep. 2021;11(1):710. Epub 2021/01/14. doi: 10.1038/s41598-020-80605-6. PubMed PMID: 33436912; PMCID: PMC7804305.

Yu L, He J, Wang L, Yi H. Inflammatory profiles revealed the dysregulation of cytokines in adult patients of HFMD. Int J Infect Dis. 2018 Nov 10. pii: S1201-9712(18)34579-X. doi: 10.1016/j.ijid.2018.11.001.

Yu L, He J, Wang L, Yi H. Incidence, etiology, and serotype spectrum analysis of adult hand, foot, and mouth disease patients: A retrospective observational cohort study in northern Zhejiang, China. Int J Infect Dis. 2019 Aug; 85:28-36.  doi: 10.1016/j.ijid.2019.05.016.   PMID: 31100417

He, J*. (2016) Function of Polycomb repressive complexes in stem cells. Front. Biol. 11:65